Opteron 2222 SE 's Advantages
Higher base frequency (3GHz vs 2.7GHz)
Lower TDP (119W vs 130W)
Intel Xeon E5 2680 's Advantages
Released 4 years and 11 months late
Higher specification of memory (3 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (32nm vs 90nm)