Opteron 3320 EE 's Advantages
Lower TDP (25W vs 225W)
AMD EPYC 7543 's Advantages
Released 8 years and 3 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.8GHz vs 1.9GHz)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)