Opteron 3320 EE 's Advantages
Lower TDP (25W vs 205W)
Xeon Platinum 8280M 's Advantages
Released 6 years late
Higher specification of memory (2933 vs 3)
Newer PCIe version (3 vs 2)
Higher base frequency (2.7GHz vs 1.9GHz)
Larger L3 cache size (38.5MB vs 8MB)
More modern manufacturing process (14nm vs 32nm)