Opteron 3380 's Advantages
Higher base frequency (2.6GHz vs 2.2GHz)
Lower TDP (65W vs 205W)
Intel Xeon Gold 5520 's Advantages
Released 11 years late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (52.5MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)