Opteron 3380 's Advantages
Lower TDP (65W vs 270W)
Intel Xeon w5 3435X 's Advantages
Released 10 years and 2 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Higher base frequency (3.1GHz vs 2.6GHz)
Larger L3 cache size (45MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)