Opteron 3380 's Advantages
Higher base frequency (2.6GHz vs 2.2GHz)
Lower TDP (65W vs 105W)
Xeon E5 2650 v4 's Advantages
Released 3 years and 3 months late
Higher specification of memory (2133 vs 3)
Newer PCIe version (3 vs 2)
Larger L3 cache size (30MB vs 8MB)
More modern manufacturing process (14nm vs 32nm)