Opteron 4334 's Advantages
Higher base frequency (3.1GHz vs 2.8GHz)
Lower TDP (95W vs 225W)
AMD EPYC 7543 's Advantages
Released 8 years and 3 months late
Higher specification of memory (3200 vs 3)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)