Opteron 4340 's Advantages
Higher base frequency (3.5GHz vs 2.25GHz)
Lower TDP (95W vs 360W)
AMD EPYC 9754 's Advantages
Released 10 years and 6 months late
Higher specification of memory (4800 vs 3)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)