Opteron 4376 HE 's Advantages
Lower TDP (65W vs 300W)
Xeon w5 3535X 's Advantages
Released 11 years and 8 months late
Higher specification of memory (4800 vs 3)
Higher base frequency (2.9GHz vs 2.6GHz)
Larger L3 cache size (52.5MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)