Opteron 4386 's Advantages
Higher base frequency (3.1GHz vs 2.9GHz)
Lower TDP (95W vs 120W)
EPYC 7272 's Advantages
Released 6 years and 8 months late
Higher specification of memory (3200 vs 3)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)