Opteron 6180 SE 's Advantages
Lower TDP (140W vs 290W)
AMD EPYC 9454P 's Advantages
Released 11 years and 9 months late
Higher specification of memory (4800 vs 1333)
Newer PCIe version (5 vs 2)
Higher base frequency (2.75GHz vs 2.5GHz)
Larger L3 cache size (256MB vs 12MB)
More modern manufacturing process (5nm vs 45nm)