Opteron 6180 SE 's Advantages
Higher base frequency (2.5GHz vs 2.25GHz)
Lower TDP (140W vs 360W)
AMD EPYC 9754 's Advantages
Released 12 years and 4 months late
Higher specification of memory (4800 vs 1333)
Newer PCIe version (5 vs 2)
Larger L3 cache size (256MB vs 12MB)
More modern manufacturing process (5nm vs 45nm)