Opteron 6272 's Advantages
Higher base frequency (2.1GHz vs 2GHz)
Lower TDP (115W vs 165W)
Intel Xeon Silver 4416 's Advantages
Released 11 years and 2 months late
Higher specification of memory (4000 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (37.5MB vs 16MB)
More modern manufacturing process (10nm vs 32nm)