Opteron 6278 's Advantages
Lower TDP (115W vs 125W)
AMD EPYC 8124P 's Advantages
Released 11 years and 4 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Higher base frequency (2.45GHz vs 2.4GHz)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)