Opteron 6278 's Advantages
Higher base frequency (2.4GHz vs 2.2GHz)
Xeon E5 2650 v4 's Advantages
Released 3 years and 10 months late
Higher specification of memory (2133 vs 3)
Newer PCIe version (3 vs 2)
Larger L3 cache size (30MB vs 8MB)
More modern manufacturing process (14nm vs 32nm)
Lower TDP (105W vs 115W)