Opteron 6376 's Advantages
Lower TDP (115W vs 210W)
Xeon w5 2545 's Advantages
Released 11 years and 9 months late
Higher specification of memory (4800 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (3.5GHz vs 2.3GHz)
Larger L3 cache size (30MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)