Opteron 6378 's Advantages
Lower TDP (115W vs 120W)
AMD EPYC 7203P 's Advantages
Released 10 years and 10 months late
Higher specification of memory (3200 vs 1866)
Newer PCIe version (4 vs 2)
Higher base frequency (2.8GHz vs 2.4GHz)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)