Opteron 6386 SE 's Advantages
Lower TDP (140W vs 210W)
AMD EPYC 9335 's Advantages
Released 11 years and 11 months late
Higher specification of memory (6000 vs 1600)
Newer PCIe version (5 vs 2)
Higher base frequency (3GHz vs 2.8GHz)
Larger L3 cache size (128MB vs 8MB)
More modern manufacturing process (4nm vs 32nm)