Opteron 8216 HE (F3) 's Advantages
Lower TDP (68W vs 280W)
AMD EPYC 7H12 's Advantages
Released 13 years and 1 months late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
Higher base frequency (2.6GHz vs 2.4GHz)
More modern manufacturing process (7nm vs 90nm)