Opteron 8216 HE (F3) 's Advantages
Lower TDP (68W vs 160W)
AMD EPYC 8224P 's Advantages
Released 17 years and 1 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
Higher base frequency (2.55GHz vs 2.4GHz)
More modern manufacturing process (5nm vs 90nm)