Opteron 8216 HE (F3) 's Advantages
Higher base frequency (2.4GHz vs 2.2GHz)
Opteron 4310 EE 's Advantages
Released 6 years and 4 months late
Higher specification of memory (1600 vs 667)
Newer PCIe version (2 vs 1)
More modern manufacturing process (32nm vs 90nm)
Lower TDP (35W vs 68W)