Opteron 8220 SE (F3) 's Advantages
Higher base frequency (2.8GHz vs 2.1GHz)
Lower TDP (120W vs 270W)
Intel Xeon Gold 6538N 's Advantages
Released 17 years and 4 months late
Higher specification of memory (5200 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (10nm vs 90nm)