Opteron 8220 SE (F3) 's Advantages
Higher specification of memory (667 vs 3)
Higher base frequency (2.8GHz vs 2.6GHz)
Opteron 3380 's Advantages
Released 6 years and 4 months late
Newer PCIe version (2 vs 1)
More modern manufacturing process (32nm vs 90nm)
Lower TDP (65W vs 120W)