Opteron 8220 's Advantages
Higher base frequency (2.8GHz vs 1.8GHz)
Intel Xeon E5 2648L v3 's Advantages
Released 7 years and 7 months late
Higher specification of memory (2133 vs 667)
Newer PCIe version (3 vs 1)
More modern manufacturing process (22nm vs 90nm)
Lower TDP (75W vs 95W)