Opteron 8222 SE 's Advantages
Higher base frequency (3GHz vs 2.75GHz)
Lower TDP (120W vs 290W)
AMD EPYC Embedded 9454 's Advantages
Released 15 years and 11 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)