Opteron 8222 's Advantages
Higher specification of memory (667 vs 3)
Higher base frequency (3GHz vs 2.6GHz)
Opteron 3380 's Advantages
Released 5 years and 4 months late
Newer PCIe version (2 vs 1)
More modern manufacturing process (32nm vs 90nm)
Lower TDP (65W vs 95W)