Opteron 8224 SE 's Advantages
Higher base frequency (3.2GHz vs 2.4GHz)
Lower TDP (120W vs 225W)
AMD EPYC 7642 's Advantages
Released 12 years late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)