Xeon E 2278GEL 's Advantages
Higher base frequency (2GHz vs 1.8GHz)
Lower TDP (35W vs 185W)
Intel Xeon Gold 6421N 's Advantages
Released 3 years and 7 months late
Higher specification of memory (4400 vs 2666)
Newer PCIe version (5 vs 3)
Larger L3 cache size (60MB vs 16MB)
More modern manufacturing process (10nm vs 14nm)