Home GPU Comparison AMD Instinct MI300X vs NVIDIA Quadro Plex 2100 S4

AMD Instinct MI300X vs NVIDIA Quadro Plex 2100 S4

We compared two Professional market GPUs: 192GB VRAM AMD Instinct MI300X and 1536MB VRAM Quadro Plex 2100 S4 to see which GPU has better performance in key specifications, benchmark tests, power consumption, etc.

Main Differences

AMD Instinct MI300X 's Advantages
Released 15 years and 5 months late
Boost Clock2100MHz
More VRAM (192GB vs 1536GB)
Larger VRAM bandwidth (5300GB/s vs 76.80GB/s)
19328 additional rendering cores
NVIDIA Quadro Plex 2100 S4 's Advantages
Lower TDP (640W vs 750W)

Score

Benchmark

FP32 (float)
AMD Instinct MI300X +47125%
163.4 TFLOPS
Quadro Plex 2100 S4
0.346 TFLOPS
VS

Graphics Card

Dec 2023
Release Date
Jul 2008
Instinct
Generation
Quadro Plex
Professional
Type
Professional
PCIe 5.0 x16
Bus Interface
PCIe 1.0 x16

Clock Speeds

1000 MHz
Base Clock
-
2100 MHz
Boost Clock
-
5200 MHz
Memory Clock
800 MHz

Memory

192GB
Memory Size
1536MB
HBM3
Memory Type
GDDR3
8192bit
Memory Bus
384bit
5300GB/s
Bandwidth
76.80GB/s

Render Config

304
Compute Units
-
-
SM Count
16
19456
Shading Units
128
880
TMUs
32
0
ROPs
24
-
-
-
-
-
-
16 KB (per CU)
L1 Cache
-
16 MB
L2 Cache
96 KB
-
-
-

Theoretical Performance

0 MPixel/s
Pixel Rate
14.40 GPixel/s
1496 GTexel/s
Texture Rate
38.40 GTexel/s
1300 TFLOPS
FP16 (half)
-
163.4 TFLOPS
FP32 (float)
345.6 GFLOPS
81.7 TFLOPS
FP64 (double)
-

Board Design

750W
TDP
640W
1000 W
Suggested PSU
1000 W
No outputs
Outputs
No outputs
None
Power Connectors
-

Graphics Processor

MI300
GPU Name
G80
-
-
-
CDNA 3.0
Architecture
Tesla
TSMC
Foundry
TSMC
5 nm
Process Size
90 nm
146 billion
Transistors
0.681 billion
1017 mm²
Die Size
484 mm²

Graphics Features

N/A
DirectX
11.1 (10_0)
N/A
OpenGL
3.3
3.0
OpenCL
1.1 (1.0)
N/A
Vulkan
N/A
-
CUDA
1.0
N/A
Shader Model
4.0

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