AMD Radeon Pro WX 9100 's Advantages
More VRAM (16GB vs 4GB)
Larger VRAM bandwidth (483.8GB/s vs 224.0GB/s)
2816 additional rendering cores
AMD Radeon Pro 5300 's Advantages
Released 3 years and 1 months late
Boost Clock has increased by 10% (1650MHz vs 1500MHz)
Lower TDP (85W vs 230W)