AMD EPYC 7251 's Advantages
Released 8 years late
Higher specification of memory (2400 vs 1333)
Newer PCIe version (3 vs 2)
Larger L3 cache size (32MB vs 6MB)
More modern manufacturing process (14nm vs 45nm)
Opteron 1389 's Advantages
Higher base frequency (2.9GHz vs 2.1GHz)
Lower TDP (115W vs 120W)