AMD EPYC 9454 's Advantages
Released 10 years and 8 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 3)
Higher base frequency (2.75GHz vs 2.7GHz)
Larger L3 cache size (256MB vs 20MB)
More modern manufacturing process (5nm vs 32nm)
Intel Xeon E5 2680 's Advantages
Lower TDP (130W vs 290W)