AMD EPYC 9454 's Advantages
Released 10 years late
Higher specification of memory (4800 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (2.75GHz vs 1.8GHz)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)
Opteron 6366 HE 's Advantages
Lower TDP (85W vs 290W)