AMD EPYC 9645 's Advantages
Released 13 years and 8 months late
Higher specification of memory (6000 vs 1333)
Newer PCIe version (5 vs 2)
Larger L3 cache size (256MB vs 12MB)
More modern manufacturing process (3nm vs 45nm)
Opteron 6180 SE 's Advantages
Higher base frequency (2.5GHz vs 2.3GHz)
Lower TDP (140W vs 320W)