AMD EPYC 9754S 's Advantages
Released 14 years and 3 months late
Higher specification of memory (4800 vs 1333)
Newer PCIe version (5 vs 2)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 45nm)
Xeon W5580 's Advantages
Higher base frequency (3.2GHz vs 2.25GHz)
Lower TDP (130W vs 360W)