Intel Xeon E3 1225 v5 's Advantages
Higher base frequency (3.3GHz vs 2.2GHz)
Lower TDP (80W vs 330W)
Xeon 6780E 's Advantages
Released 8 years and 8 months late
Higher specification of memory (6400 vs 2133)
Newer PCIe version (5 vs 3)
Larger L3 cache size (108MB vs 8MB)
More modern manufacturing process (5nm vs 14nm)