Intel Xeon E3 1280 v5 's Advantages
Higher base frequency (3.7GHz vs 2.3GHz)
Lower TDP (80W vs 225W)
AMD EPYC 7643 's Advantages
Released 5 years and 5 months late
Higher specification of memory (3200 vs 4)
Newer PCIe version (4 vs 3)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (7nm vs 14nm)