Intel Xeon E3 1280 v5 's Advantages
Higher base frequency (3.7GHz vs 3.4GHz)
Lower TDP (80W vs 250W)
Intel Xeon W 3335 's Advantages
Released 5 years and 9 months late
Higher specification of memory (3200 vs 4)
Newer PCIe version (4 vs 3)
Larger L3 cache size (24MB vs 8MB)
More modern manufacturing process (10nm vs 14nm)