Intel Xeon E5 4620 's Advantages
Higher base frequency (2.2GHz vs 2.1GHz)
Lower TDP (130W vs 250W)
Intel Xeon Platinum 9221 's Advantages
Released 6 years and 11 months late
Higher specification of memory (2933 vs 3)
Larger L3 cache size (71.5MB vs 16MB)
More modern manufacturing process (14nm vs 32nm)