Intel Xeon Gold 6421N 's Advantages
Released 8 years and 4 months late
Higher specification of memory (4400 vs 2133)
Newer PCIe version (5 vs 3)
Larger L3 cache size (60MB vs 20MB)
More modern manufacturing process (10nm vs 22nm)
Intel Xeon E5 2643 v3 's Advantages
Higher base frequency (3.4GHz vs 1.8GHz)
Lower TDP (135W vs 185W)