Intel Xeon Gold 6421N 's Advantages
Released 10 years and 2 months late
Higher specification of memory (DDR5-4400 vs DDR3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (60MB vs 8MB)
Opteron 6380 's Advantages
Higher base frequency (2.5GHz vs 1.8GHz)
Lower TDP (115W vs 185W)