Opteron 1381 's Advantages
Higher base frequency (2.5GHz vs 2.4GHz)
Lower TDP (115W vs 130W)
AMD EPYC 7303 's Advantages
Released 14 years and 3 months late
Higher specification of memory (3200 vs 1333)
Newer PCIe version (4 vs 2)
Larger L3 cache size (64MB vs 6MB)
More modern manufacturing process (7nm vs 45nm)