Opteron 2216 (F3) 's Advantages
Higher base frequency (2.4GHz vs 2.25GHz)
Lower TDP (95W vs 360W)
AMD EPYC 9754 's Advantages
Released 16 years and 10 months late
Higher specification of memory (4800 vs 2)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)