Opteron 2216 HE (F2) 's Advantages
Lower TDP (68W vs 130W)
Xeon W5580 's Advantages
Released 2 years and 7 months late
Higher specification of memory (1333 vs 2)
Newer PCIe version (2 vs 1)
Higher base frequency (3.2GHz vs 2.4GHz)
More modern manufacturing process (45nm vs 90nm)