Opteron 2220 's Advantages
Lower TDP (95W vs 300W)
AMD EPYC 9365 's Advantages
Released 17 years and 8 months late
Higher specification of memory (6000 vs 2)
Newer PCIe version (5 vs 1)
Higher base frequency (3.4GHz vs 2.8GHz)
More modern manufacturing process (4nm vs 90nm)