Opteron 2220 's Advantages
Higher base frequency (2.8GHz vs 2.7GHz)
Lower TDP (95W vs 130W)
Intel Xeon E5 4650 's Advantages
Released 5 years and 3 months late
Higher specification of memory (3 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (32nm vs 90nm)