Opteron 2220 's Advantages
Lower TDP (95W vs 270W)
Intel Xeon w5 3425 's Advantages
Released 16 years late
Higher specification of memory (4800 vs 2)
Newer PCIe version (5 vs 1)
Higher base frequency (3.2GHz vs 2.8GHz)
More modern manufacturing process (10nm vs 90nm)