Opteron 6168 's Advantages
Lower TDP (115W vs 155W)
AMD EPYC 7452 's Advantages
Released 9 years and 5 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.2GHz vs 1.9GHz)
Larger L3 cache size (128MB vs 12MB)
More modern manufacturing process (7nm vs 45nm)