Opteron 6380 's Advantages
Higher base frequency (2.5GHz vs 2GHz)
Lower TDP (115W vs 205W)
Intel Xeon Gold 6330 's Advantages
Released 8 years and 5 months late
Higher specification of memory (3200 vs 1866)
Newer PCIe version (4 vs 2)
Larger L3 cache size (42MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)