Opteron 6380 's Advantages
Released 6 years and 3 months late
Higher specification of memory (1866 vs 2)
Newer PCIe version (2 vs 1)
Higher base frequency (2.5GHz vs 2.4GHz)
More modern manufacturing process (32nm vs 90nm)
Opteron 2216 HE (F3) 's Advantages
Lower TDP (68W vs 115W)